Product Datasheet  
MKL1 Antibody  
Catalog Number: 34018  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q969V6
    NCBI Gene ID: 57591
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from N-terminal of human MKL1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Myocardin-related transcription factor A; MRTF-A; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total MKL1 protein.
  • Applications：  
  • WB
  • Background：  
  • Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.

    Ma Z., Nat. Genet. 28:220-221(2001).
    Mercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).
    Nagase T., DNA Res. 7:65-73(2000).



 
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