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TF3B Antibody

Catalog Number:

34013
other_names: TFIIIB90; hTFIIIB90; B-related factor 1; BRF-1; hBRF

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q92994
NCBI Gene ID: 2972

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TF3B.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TF3B protein.

Applications:

WB IHC IF

Background:

General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.

Wang Z., Proc. Natl. Acad. Sci. U.S.A. 92:7026-7030(1995).
Mital R., Mol. Cell. Biol. 16:7031-7042(1996).
McCulloch V., EMBO J. 19:4134-4143(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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