Product Datasheet
TF3B Antibody
Catalog Number: 34013
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q92994
NCBI Gene ID: 2972
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human TF3B.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- TFIIIB90; hTFIIIB90; B-related factor 1; BRF-1; hBRF
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total TF3B protein.
- Background:
- General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
Wang Z., Proc. Natl. Acad. Sci. U.S.A. 92:7026-7030(1995).
Mital R., Mol. Cell. Biol. 16:7031-7042(1996).
McCulloch V., EMBO J. 19:4134-4143(2000).
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