STRAD Antibody

Catalog Number:

33947

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q7RTN6
NCBI Gene ID: 92335

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human STRAD.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STRAD protein.

Applications:

WB

Background:

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Scanlan M.J., Cancer Immun. 1:4-4(2001).
Ota T., Nat. Genet. 36:40-45(2004).
Baas A.F., EMBO J. 22:3062-3072(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF