Product Datasheet  
STRAD Antibody  
Catalog Number: 33947  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q7RTN6
    NCBI Gene ID: 92335
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human STRAD.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • STE20-related adapter protein; STRAD alpha; Serologically defined breast cancer antigen NY-BR-96; STRAD; LYK5
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total STRAD protein.
  • Applications：  
  • WB
  • Background：  
  • Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

    Scanlan M.J., Cancer Immun. 1:4-4(2001).
    Ota T., Nat. Genet. 36:40-45(2004).
    Baas A.F., EMBO J. 22:3062-3072(2003).



 
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