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TNFAIP8L2 Antibody

Catalog Number:

33938
other_names: Tumor necrosis factor; alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2; TIPE2; Inflammation factor protein 20

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q6P589
NCBI Gene ID: 79626

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TNFAIP8L2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNFAIP8L2 protein.

Applications:

WB

Background:

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis By similarity.

Chen Y.H., Cell 133:415-426(2008).
Sugano S., Nat. Genet. 36:40-45(2004).
Schupp I., BMC Genomics 8:399-399(2007)

References:

appl_detail:

Western blotting: 1:500~1:3000

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