Product Datasheet
TNFAIP8L2 Antibody
Catalog Number: 33938
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q6P589
NCBI Gene ID: 79626
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human TNFAIP8L2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Tumor necrosis factor; alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2; TIPE2; Inflammation factor protein 20
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total TNFAIP8L2 protein.
- Background:
- Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis By similarity.
Chen Y.H., Cell 133:415-426(2008).
Sugano S., Nat. Genet. 36:40-45(2004).
Schupp I., BMC Genomics 8:399-399(2007)
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