ZFHX3 Antibody

Catalog Number:	33910
other_names:	Zinc finger homeodomain protein 3; ZFH-3; Alpha-fetoprotein enhancer-binding protein; AT motif-binding factor; AT-binding transcription factor 1
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot: Q15911 NCBI Gene ID: 463
Form of Antibody:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Immunogen:	Synthesized peptide derived from internal of human ZFHX3.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity/Sensitivity:	The antibody detects endogenous levels of total ZFHX3 protein.
Applications:	IHC
Background:	Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer. Miura Y., J. Biol. Chem. 270:26840-26848(1995). Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991). Martin J., Nature 432:988-994(2004).
References:
appl_detail:	Immunohistochemistry: 1:50~1:100
	Datasheet PDF

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