Product Datasheet  
ZFHX3 Antibody  
Catalog Number: 33910  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q15911
    NCBI Gene ID: 463
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human ZFHX3.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Zinc finger homeodomain protein 3; ZFH-3; Alpha-fetoprotein enhancer-binding protein; AT motif-binding factor; AT-binding transcription factor 1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ZFHX3 protein.
  • Applications：  
  • IHC
  • Background：  
  • Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer.

    Miura Y., J. Biol. Chem. 270:26840-26848(1995).
    Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991).
    Martin J., Nature 432:988-994(2004).



 
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