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NR1I3 Antibody

Catalog Number:

33887
other_names: CAR; Constitutive androstane receptor; Orphan nuclear receptor MB67; Orphan nuclear receptor NR1I3;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q14994
NCBI Gene ID: 9970

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human NR1I3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NR1I3 protein.

Applications:

WB

Background:

Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.

Baes M., Mol. Cell. Biol. 14:1544-1552(1994).
Choi H.S., J. Steroid Biochem. Mol. Biol. 56:23-30(1996).
Xu R.X., Mol. Cell 16:919-928(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

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