Product Datasheet
NR1I3 Antibody
Catalog Number: 33887
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q14994
NCBI Gene ID: 9970
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human NR1I3.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CAR; Constitutive androstane receptor; Orphan nuclear receptor MB67; Orphan nuclear receptor NR1I3;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total NR1I3 protein.
- Background:
- Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Baes M., Mol. Cell. Biol. 14:1544-1552(1994).
Choi H.S., J. Steroid Biochem. Mol. Biol. 56:23-30(1996).
Xu R.X., Mol. Cell 16:919-928(2004).
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