MAD4 Antibody

Catalog Number:

33882

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q14582
NCBI Gene ID: 10608

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MAD4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAD4 protein.

Applications:

IHC

Background:

Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation By similarity.

Hillier L.W., Nature 434:724-731(2005).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Pribill I., Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF