Product Datasheet  
MAD4 Antibody  
Catalog Number: 33882  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q14582
    NCBI Gene ID: 10608
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human MAD4.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Max-associated protein 4; MAX dimerization protein 4;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total MAD4 protein.
  • Applications：  
  • IHC
  • Background：  
  • Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation By similarity.

    Hillier L.W., Nature 434:724-731(2005).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Pribill I., Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.



 
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