hnRNP F Antibody

Catalog Number:

33806

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P52597
NCBI Gene ID: 3185

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human hnRNP F.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total hnRNP F protein.

Applications:

WB

Background:

Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.

Matunis M.J., Nucleic Acids Res. 22:1059-1067(1994).
Honore B., J. Biol. Chem. 270:28780-28789(1995).
McDonald H., Genomics 13:344-348(1992).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF