Product Datasheet
hnRNP F Antibody
Catalog Number: 33806
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P52597
NCBI Gene ID: 3185
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human hnRNP F.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- HNRPF; ROF; heterogeneous nuclear ribonucleoprotein F;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total hnRNP F protein.
- Background:
- Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
Matunis M.J., Nucleic Acids Res. 22:1059-1067(1994).
Honore B., J. Biol. Chem. 270:28780-28789(1995).
McDonald H., Genomics 13:344-348(1992).
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