ERCC5 Antibody

Catalog Number:

33738

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P28715
NCBI Gene ID: 2073

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ERCC5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ERCC5 protein.

Applications:

WB

Background:

Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.

Scherly D., Nature 363:182-185(1993).
Shiomi T., Mutat. Res. 314:167-175(1994).
Macinnes M.A., Mol. Cell. Biol. 13:6393-6402(1993).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF