Product Datasheet  
ERCC5 Antibody  
Catalog Number: 33738  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P28715
    NCBI Gene ID: 2073
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human ERCC5.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:500~1:3000

  • other_names：  
  • DNA excision repair protein ERCC-5; DNA-repair protein complementing XP-G cells; ERCC5; XPGC; Xeroderma pigmentosum group G complementing protein
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ERCC5 protein.
  • Applications：  
  • WB
  • Background：  

  • Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.

    Scherly D., Nature 363:182-185(1993).
    Shiomi T., Mutat. Res. 314:167-175(1994).
    Macinnes M.A., Mol. Cell. Biol. 13:6393-6402(1993).




 
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