ITPKB Antibody

Catalog Number:

33734

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P27987
NCBI Gene ID: 3707

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human ITPKB.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ITPKB protein.

Applications:

WB

Background:

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

Dewaste V., Biochem. Biophys. Res. Commun. 291:400-405(2002).
Bertsch U., Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
Gregory S.G., Nature 441:315-321(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF