Product Datasheet  
ITPKB Antibody  
Catalog Number: 33734  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P27987
    NCBI Gene ID: 3707
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from Internal of human ITPKB.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Inositol 1; 4; 5-trisphosphate 3-kinase B; Inositol-trisphosphate 3-kinase B; InsP 3-kinase B
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ITPKB protein.
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

    Dewaste V., Biochem. Biophys. Res. Commun. 291:400-405(2002).
    Bertsch U., Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
    Gregory S.G., Nature 441:315-321(2006).



 
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