COT2 Antibody

Catalog Number:

33724

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P24468
NCBI Gene ID: 7026

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human COT2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total COT2 protein.

Applications:

WB IF

Background:

Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.

Ladias J.A.A., Science 251:561-565(1991).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Wang L.H., Gene Expr. 1:207-216(1991).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF