Product Datasheet
COT2 Antibody
Catalog Number: 33724
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P24468
NCBI Gene ID: 7026
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human COT2.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
- other_names:
- COUP transcription factor 2; COUP-TF2; COUP-TF II; Nuclear receptor subfamily 2 group F member 2; Apolipoprotein AI regulatory protein 1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total COT2 protein.
- Background:
- Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.
Ladias J.A.A., Science 251:561-565(1991).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Wang L.H., Gene Expr. 1:207-216(1991).
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