DIL-2 Antibody

Catalog Number:

34117

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9ULW0
NCBI Gene ID: 22974

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DIL-2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DIL-2 protein.

Applications:

WB IHC

Background:

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

Manda R., Genomics 61:5-14(1999).
Zhang Y., Cytogenet. Cell Genet. 84:182-183(1999).
Wang Y., J. Immunol. 169:1102-1109(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF