Product Datasheet
DIL-2 Antibody
Catalog Number: 34117
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9ULW0
NCBI Gene ID: 22974
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human DIL-2.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- C20orf1; C20orf2; DIL-2; DIL2; Differentially expressed in lung cells 2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total DIL-2 protein.
- Background:
- Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Manda R., Genomics 61:5-14(1999).
Zhang Y., Cytogenet. Cell Genet. 84:182-183(1999).
Wang Y., J. Immunol. 169:1102-1109(2002).
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