SP3/4 Antibody

Catalog Number:

33846

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q02447/Q02446
NCBI Gene ID: 6670/6671

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human SP3/4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SP3/4 protein.

Applications:

WB

Background:

Transcriptional factor that can act as an activator or repressor depending on isoform and/orpost-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping.

Pan H., Genomics 77:58-64(2001).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF