Product Datasheet
SP3/4 Antibody
Catalog Number: 33846
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q02447/Q02446
NCBI Gene ID: 6670/6671
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human SP3/4.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- LAG1 longevity assurance; SP260; TMSG1; Tumor metastasis-suppressor gene 1 protein;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total SP3/4 protein.
- Background:
- Transcriptional factor that can act as an activator or repressor depending on isoform and/orpost-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping.
Pan H., Genomics 77:58-64(2001).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).
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