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CD2L1Antibody

Catalog Number:

33712
other_names: CD2L1; CDC2L1; CDK11; CLK-1; Cell division cycle 2-like 1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P21127
NCBI Gene ID: 984

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human CD2L1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CD2L1 protein.

Applications:

WB

Background:

Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform mayact as a negative regulator of normal cell cycle progression.

Bunnell B.A., Proc. Natl. Acad. Sci. U.S.A. 87:7467-7471(1990).
Eipers P.G., Genomics 13:613-621(1992).
Xiang J., J. Biol. Chem. 269:15786-15794(1994).

References:

appl_detail:

Western blotting: 1:500~1:3000

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