Product Datasheet
CD2L1Antibody
Catalog Number: 33712
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P21127
NCBI Gene ID: 984
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human CD2L1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- CD2L1; CDC2L1; CDK11; CLK-1; Cell division cycle 2-like 1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CD2L1 protein.
- Background:
- Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform mayact as a negative regulator of normal cell cycle progression.
Bunnell B.A., Proc. Natl. Acad. Sci. U.S.A. 87:7467-7471(1990).
Eipers P.G., Genomics 13:613-621(1992).
Xiang J., J. Biol. Chem. 269:15786-15794(1994).
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