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EGR1/2 Antibody

Catalog Number:

33701
other_names: AT225; EGR-1; Early growth response protein 1; KROX-24; Krox-24 protein

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P18146/P11161
NCBI Gene ID: 1958/1959

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human EGR1/2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EGR1/2 protein.

Applications:

WB

Background:

Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

Suggs S.V., Nucleic Acids Res. 18:4283-4283(1990).
Shimizu N., J. Biochem. 111:272-277(1992).
Wright J.J., Science 248:588-591(1990).

References:

appl_detail:

Western blotting: 1:500~1:3000

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