Product Datasheet
EGR1/2 Antibody
Catalog Number: 33701
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P18146/P11161
NCBI Gene ID: 1958/1959
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human EGR1/2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- AT225; EGR-1; Early growth response protein 1; KROX-24; Krox-24 protein
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total EGR1/2 protein.
- Background:
- Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
Suggs S.V., Nucleic Acids Res. 18:4283-4283(1990).
Shimizu N., J. Biochem. 111:272-277(1992).
Wright J.J., Science 248:588-591(1990).
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