SPI1 Antibody

Catalog Number:

33699

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P17947
NCBI Gene ID: 6688

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SPI1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SPI1 protein.

Applications:

WB

Background:

Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing By similarity.

Ray D., Oncogene 5:663-668(1990).
Rao S., J. Biol. Chem. 274:11115-11124(1999).
Mao S., Mol. Cell. Biol. 19:3635-3644(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF