Product Datasheet  
SPI1 Antibody  
Catalog Number: 33699  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P17947
    NCBI Gene ID: 6688
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human SPI1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500~1:3000

  • other_names：  
  • 31 kDa transforming protein; SPI1; transcription factor PU.1;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total SPI1 protein.
  • Applications：  
  • WB
  • Background：  

  • Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing By similarity.

    Ray D., Oncogene 5:663-668(1990).
    Rao S., J. Biol. Chem. 274:11115-11124(1999).
    Mao S., Mol. Cell. Biol. 19:3635-3644(1999).




 
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