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UBF1 Antibody

Catalog Number:

33692
other_names: Autoantigen NOR-90; Nucleolar transcription factor 1; TCFUBF; UBF-1; UBF1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P17480
NCBI Gene ID: 7343

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human UBF1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBF1 protein.

Applications:

WB IHC

Background:

Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.

Jantzen H.M., Nature 344:830-836(1990).
Chan E.K.L., J. Exp. Med. 174:1239-1244(1991).
Molina H., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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