Product Datasheet  
UBF1 Antibody  
Catalog Number: 33692  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P17480
    NCBI Gene ID: 7343
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human UBF1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Autoantigen NOR-90; Nucleolar transcription factor 1; TCFUBF; UBF-1; UBF1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total UBF1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.

    Jantzen H.M., Nature 344:830-836(1990).
    Chan E.K.L., J. Exp. Med. 174:1239-1244(1991).
    Molina H., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).



 
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