EGR2 Antibody

Catalog Number:

33670

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P11161
NCBI Gene ID: 1959

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human EGR2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EGR2 protein.

Applications:

WB

Background:

Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Joseph L.J., Proc. Natl. Acad. Sci. U.S.A. 85:7164-7168(1988).
Warner L.E., Nat. Genet. 18:382-384(1998).
Bechtel S., BMC Genomics 8:399-399(2007).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF