Product Datasheet  
EGR2 Antibody  
Catalog Number: 33670  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P11161
    NCBI Gene ID: 1959
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human EGR2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • AT591; CMT1D; CMT4E; DKFZp686J1957; early growth response 2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total EGR2 protein.
  • Applications：  
  • WB
  • Background：  
  • Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

    Joseph L.J., Proc. Natl. Acad. Sci. U.S.A. 85:7164-7168(1988).
    Warner L.E., Nat. Genet. 18:382-384(1998).
    Bechtel S., BMC Genomics 8:399-399(2007).




 
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