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HEXB Antibody

Catalog Number:

33657
other_names: Beta-hexosaminidase beta chain [Precursor]; EC 3.2.1.52; N-acetyl-beta-glucosaminidase; Beta-N-acetylhexosaminidase; Hexosaminidase B

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P07686
NCBI Gene ID: 3074

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human HEXB.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HEXB protein.

Applications:

WB IHC

Background:

Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.

Korneluk R.G., J. Biol. Chem. 261:8407-8413(1986).
Neote K., Genomics 3:279-286(1988).
Proia R.L., Proc. Natl. Acad. Sci. U.S.A. 85:1883-1887(1988).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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