Product Datasheet  
HEXB Antibody  
Catalog Number: 33657  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P07686
    NCBI Gene ID: 3074
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human HEXB.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Beta-hexosaminidase beta chain [Precursor]; EC 3.2.1.52; N-acetyl-beta-glucosaminidase; Beta-N-acetylhexosaminidase; Hexosaminidase B
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total HEXB protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.

    Korneluk R.G., J. Biol. Chem. 261:8407-8413(1986).
    Neote K., Genomics 3:279-286(1988).
    Proia R.L., Proc. Natl. Acad. Sci. U.S.A. 85:1883-1887(1988).



 
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