TFIP8 Antibody

Catalog Number:

33631

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O95379
NCBI Gene ID: 25816

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TFIP8.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TFIP8 protein.

Applications:

WB IHC IF

Background:

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Horrevoets A.J.G., Blood 93:3418-3431(1999).
Kumar D., J. Biol. Chem. 275:2973-2978(2000).
You Z., J. Biol. Chem. 276:26398-26404(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF