Product Datasheet  
TFIP8 Antibody  
Catalog Number: 33631  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O95379
    NCBI Gene ID: 25816
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human TFIP8.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • Tumor necrosis factor; alpha-induced protein 8; Head and neck tumor and metastasis-related protein; TNF-induced protein GG2-1; SCC-S2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TFIP8 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

    Horrevoets A.J.G., Blood 93:3418-3431(1999).
    Kumar D., J. Biol. Chem. 275:2973-2978(2000).
    You Z., J. Biol. Chem. 276:26398-26404(2001).



 
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