DNA Polymerase θ Antibody

Catalog Number:

33611

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75417
NCBI Gene ID: 10721

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DNA Polymerase θ.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNA Polymerase θ protein.

Applications:

IHC

Background:

Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links.

Sharief F.S., Genomics 59:90-96(1999).
Harris P.V., Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF