Product Datasheet  
DNA Polymerase θ Antibody  
Catalog Number: 33611  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O75417
    NCBI Gene ID: 10721
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human DNA Polymerase θ.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • DNA polymerase theta; EC 2.7.7.7; DNA polymerase eta; POLQ; POLH
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total DNA Polymerase θ protein.
  • Applications：  
  • IHC
  • Background：  
  • Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links.

    Sharief F.S., Genomics 59:90-96(1999).
    Harris P.V., Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.



 
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