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LAT3 Antibody

Catalog Number:

33609
other_names: L-type amino acid transporter 3; LAT3; large neutral amino acids transporter small subunit 3; prostate cancer overexpressed gene 1 protein; solute carrier family 43 member 1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75387
NCBI Gene ID: 8501

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human LAT3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LAT3 protein.

Applications:

WB

Background:

Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.

Cole K.A., Genomics 51:282-287(1998).
Babu E., J. Biol. Chem. 278:43838-43845(2003).
Chuaqui R.F., Urology 50:302-307(1997).

References:

appl_detail:

Western blotting: 1:500~1:3000

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