Product Datasheet
LAT3 Antibody
Catalog Number: 33609
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O75387
NCBI Gene ID: 8501
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human LAT3.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- L-type amino acid transporter 3; LAT3; large neutral amino acids transporter small subunit 3; prostate cancer overexpressed gene 1 protein; solute carrier family 43 member 1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total LAT3 protein.
- Background:
- Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.
Cole K.A., Genomics 51:282-287(1998).
Babu E., J. Biol. Chem. 278:43838-43845(2003).
Chuaqui R.F., Urology 50:302-307(1997).
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