TNF12 Antibody

Catalog Number:

33585

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O43508
NCBI Gene ID: 8742

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TNF12.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNF12 protein.

Applications:

WB IHC IF

Background:

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).
Marsters S.A., Curr. Biol. 8:525-528(1998).
Clark H.F., Genome Res. 13:2265-2270(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF