Product Datasheet  
TNF12 Antibody  
Catalog Number: 33585  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O43508
    NCBI Gene ID: 8742
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human TNF12.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • Tumor necrosis factor ligand superfamily member 12; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand; Tumor necrosis factor ligand superfamily member 12
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TNF12 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

    Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).
    Marsters S.A., Curr. Biol. 8:525-528(1998).
    Clark H.F., Genome Res. 13:2265-2270(2003).



 
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