M3K13 Antibody

Catalog Number:

33582

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O43283
NCBI Gene ID: 9175

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human M3K13.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total M3K13 protein.

Applications:

WB

Background:

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Sakuma H., J. Biol. Chem. 272:28622-28629(1997).
Schultz S.J., Cell Growth Differ. 4:821-830(1993).
Ikeda A., FEBS Lett. 488:190-195(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF