KLF11 Antibody

Catalog Number:

33571

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O14901
NCBI Gene ID: 8462

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human KLF11.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KLF11 protein.

Applications:

WB

Background:

Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.

Cook T., J. Biol. Chem. 273:25929-25936(1998).
Asano H., Mol. Cell. Biol. 19:3571-3579(1999).
Neve B., Proc. Natl. Acad. Sci. U.S.A. 102:4807-4812(2005).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF