Product Datasheet  
KLF11 Antibody  
Catalog Number: 33571  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O14901
    NCBI Gene ID: 8462
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from Internal of human KLF11.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • KLF11; Krueppel-like factor 11; TGFB-inducible early growth response protein 2; TIEG-2; transforming growth factor-beta-inducible early growth response protein 2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total KLF11 protein.
  • Applications：  
  • WB
  • Background：  
  • Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.

    Cook T., J. Biol. Chem. 273:25929-25936(1998).
    Asano H., Mol. Cell. Biol. 19:3571-3579(1999).
    Neve B., Proc. Natl. Acad. Sci. U.S.A. 102:4807-4812(2005).



 
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