Tyrosinase Antibody

Catalog Number:

33534

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P14679
NCBI Gene ID: 7299

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human tyrosinase.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total tyrosinase protein.

Applications:

WB

Background:

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.

Patricia Giraldo, Nucleic Acids Res., Nov 2003; 31: 6290 - 6305.
R Halaban, J. Cell Biol., Aug 1983; 97: 480.
Hee-Young Park, J. Biol. Chem., Jun 1999; 274: 16470.
BB Fuller, J. Biol. Chem., Mar 1987; 262: 4024 - 4033.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF