Product Datasheet  
Tyrosinase Antibody  
Catalog Number: 33534  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P14679
    NCBI Gene ID: 7299
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from Internal of human tyrosinase.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • TYR; EC 1.14.18.1; Monophenol monooxygenase; Tumor rejection antigen AB; SK29-AB
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total tyrosinase protein.
  • Applications：  
  • WB
  • Background：  
  • This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.

    Patricia Giraldo, Nucleic Acids Res., Nov 2003; 31: 6290 - 6305.
    R Halaban, J. Cell Biol., Aug 1983; 97: 480.
    Hee-Young Park, J. Biol. Chem., Jun 1999; 274: 16470.
    BB Fuller, J. Biol. Chem., Mar 1987; 262: 4024 - 4033.



 
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